Research - A/Professor Dutton Orthopaedic Doctor & Surgeon in Singapore
A/Professor Andrew Quoc Dutton’s passion for orthopaedic medicine and surgery has manifested itself in more than just his clinical practice. Dedicated to improving medical and surgical techniques, A/Professor Dutton continues to write articles and publish studies in reputable publications on orthopaedic medicine and surgery.
(1) Cemented Cruciate-Retaining Total Knee Arthroplasty in Osteoarthritis: A Comparison of Pegged and Stemmed Tibial Designs.
In this study published in The Journal of Knee Surgery (2014), A/Professor Andrew Quoc Dutton and his colleagues compared the clinical, functional, and radiographic outcomes between pegged and stemmed tibial designs in patients who are undergoing primary cemented total knee arthroplasty (TKA) for osteoarthritis.
The outcomes were measured using two different tools – the knee society score and knee injury and osteoarthritis outcome score at 6, 12, and 24 months after surgery. This study was meant to reveal if there is any significant difference between the two designs mentioned above.
(2) Bicompartmental Versus Total Knee Arthroplasty for Medial and Patellofemoral Osteoarthritis
In this comparative study published in the Journal of Orthopaedic Surgery (Hong Kong) in December of 2013, A/Professor Andrew Quoc Dutton along with 3 other colleagues measure the short -term outcome of Bicompartmental Knee Arthroplasty (BKA) against Total Knee Arthroplasty (TKA) in patients with medial and patellofemoral knee osteoarthritis.
The study noted any differences in characteristics such as the age, operating time, intra-operative blood loss, and range of movement.
Link: https://www.ncbi.nlm.nih.gov/pubmed/24366784
(3) Bicompartmental Versus Total Knee Arthroplasty for Medio-Patellofemoral Osteoarthritis: A Comparison of Early Clinical and Functional Outcomes.
A/Professor Andrew Quoc Dutton, along with three other colleagues compared the clinical and functional outcomes between bicompartmental and total knee arthroplasty as an intervention to medio-patellofemoral osteoarthritis. This study was published in The Journal of Knee Surgery in 2013.
Link: https://www.ncbi.nlm.nih.gov/pubmed/23575564
(4) Enhancement of Meniscal Repair in the Avascular Zone Using Mesenchymal Stem Cells in a Porcine Model.
This study published in The Journal of Bone and Joint Surgery in 2010. A/Professor Dutton along with his collagues looked into the effects of mesenchymal stem cells (MSCs) to improve meniscal repair in this non-vascularised area.
Using adult pigs as subjects, the group assessed histologic and microscopic findings to measure the extent of healing between three experimental groups comprising, untreated subjects, a group treated with sutures and fibrin glue, and another using sutures, fibrin glue and MSCs.
Link: https://www.ncbi.nlm.nih.gov/pubmed/20044699
(5) Computer-Assisted Minimally Invasive Total Knee Arthroplasty Compared with Standard Total Knee Arthroplasty. Surgical technique.
This study published in The Journal of Bone and Joint Surgery in 2009 looked into the main advantage of computer-assisted minimally invasive total knee arthroplasty (TKA) against the conventional approach.
The study revealed improved component alignment from minimally invasive TKA involving computer navigation. Despite increased operative time it had significantly less blood loss, good postoperative radiographic prosthesis alignment compared to conventional knee replacement procedures, and increased functional recovery during the first month after surgery.
Link: https://www.ncbi.nlm.nih.gov/pubmed/19255204
(6) Computer-Assisted Minimally Invasive Total Knee Arthroplasty Compared with Standard Total Knee Arthroplasty. A Prospective, Randomized Study.
The study revealed that minimally invasive computer-assisted total knee arthroplasty (TKA) has a significantly longer operative time, but with less blood loss compared to the conventional techqnique. However, study participants were discharged early with good functional recovery during the first month postoperatively. They also showd good post-operative alignment without increased short-term complications.
This research by Dr. Andrew Quoc Dutton and his colleagues The Journal of Bone and Joint Surgery in 2008.
Link: https://www.ncbi.nlm.nih.gov/pubmed/18171951
